Grapefruit and medication: a dangerous combination for older people

Although they are good for health, they can pose a serious risk for older people. The reason is the interaction of this fruit with certain medicines that are often used by the elderly.

Why can grapefruit be dangerous to older people?

The compounds in the grapefruit operate the enzyme CYP3A4 in the digestive tract. This enzyme is responsible for the metabolism of many drugs in the body. When this enzyme activity is disrupted:

• The concentration of medicines in the blood can reach a dangerously high level
• Increases the risk of side effects
• Medication of medication may be impaired

Dangerous drug combinations with grapefruit

1. Statins (cholesterol reduction drugs)

• Increases in the concentration of medicines in the blood
• Muscle aches may occur
• Increased risk of liver damage

2. Antihistamines

• The sedative effect is strengthened
• Adverse reactions may occur
• Increased drowsiness

3. Anticoagulants (Blood Liquidation Medicines)

• Increased risk of bleeding
• Blood coagulation is impaired
• Can be dangerous before surgery

4. Medicines for high blood pressure

• Excessive drop in blood pressure
• Dizziness may occur
• The risk of fainting is increased

5. Medicines for anxiety and insomnia

• The effectiveness of the drug is impaired
• May occur in an unexpected reaction
• Increases the risk of side effects

Nutrition Specialist Connie Elik emphasizes:

• Even a small amount of grapefruit or its juice can cause a negative reaction
• The reaction can occur even after a few hours
• The effect can last up to 24 hours

Recommendations

What to do with the use of these medicines:

1. To completely give up grapefruit and their juice
2. Read the medicine leaflets
3. Consult with a doctor or pharmacist
4. Choose alternative citrus fruits

Alternatives to grapefruits:

• Oranges
• Mandarins
• Lemon
• Lyme

It is important to understand that these recommendations are preventive and intended to ensure safe use of medicines. If any questions or doubts arise, it is necessary to consult health care professionals.

Source:

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