A new investigation has created infrared light -activated therapy that selectively eliminates cancer cells without affecting healthy tissues.
A new published in Angewandte Chemie International Edition created a new light -activated therapy which can revolutionize the treatment of aggressive breast cancer.
Led by husband and wife Richard and Sophia Lunt and Chemistry Professor Vincent Lavallo, the team developed a promising compound known as know of Cianina-Carborano.
These new compounds are at the center of a refined approach to photodynamic therapy (PDT), a method of treatment that Uses light -sensitive chemicals and light directed to destroy cancer cells. Rat tests showed a strong potential, with the elimination of metastatic breast cancer tumors virtually without side effects.
“Our innovators of Cyanine-Chargano offer an option oriented with reduced side effects for patients with aggressive breast cancer,” said Sophia Lunt, professor of biochemistry and molecular biology at the State University of Michigan. “We hope this investigation will lead to safer and more effective therapies for patients with limited treatment options. ”
Unlike traditional PDT compounds, which remain in the body and require patients to avoid light for months, cyanine-carbored salts accumulate mainly in carcinogenic cells. When activated by near infrared light, these compounds They act as an “smart bomb”selectively killing cancer cells without attacking healthy tissues.
“After traditional PDT treatment, patients have often been in darkness for two to three months to avoid serious skin damage.“ Our compounds greatly reduce this risk”Explained Hyllana Medeiros, postdoctoral researcher at the Michigan Statual University.
Researchers intend to explore applications for Other types of cancerbased on this initial success, it refers to.
“Truly innovative discoveries that allow solutions to problems as complex as cancer require multidisciplinary teams Like ours, ”added Richard Lunt, who recalls that research combined knowledge of biology of cancer, chemistry and material science.“ This is a perfect example of what can be achieved when very different origins experts work together ”.
