Or Niklas Elmed / Nobel Prize Outreach
Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi, the 3 Nobel Prize in Medicine 2025
American and Japanese scientists and studied the peripheral immune system and paved the way for investigations into cancer treatments and autoimmune diseases. Remaining Nobel Prizes will be announced this week.
The Nobel Prize for Physiology or Medicine was today attributed to Americans Mary E. Brunkow, Fred Ramsdell and the Japanese Shimon Sakaguchi.
The trio received the work for work on peripheral immune tolerance, a way the body has to help prevent the immune system from becoming unbalanced and attack its own tissues rather than foreign invaders.
According to, the 3 scientists identified the “regulatory T cells “which work as IMMUNITY SYSTEM GUARDIANSpreventing defense cells from attacking the body’s own tissues.
“His findings were decisive for our understanding of the functioning of the immune system and why not everyone develops serious autoimmune diseases“, explicit Ole Kings, President do Committee Nobel.
The work of the three scientists thus opened the way to new investigations into peripheral immune toleranceessential for the development of Treatments against cancer and autoimmune diseases.
Researchers will formally receive the prize, officially known as the Nobel Prize for Physiology or Medicine, during a ceremony to be held on the day December 10th.
This is the first of the Nobel Prize to be announced, in the coming days followed the awards related to physics, chemistry, literature, economic and peace sciences.
The Nobel Prizes, created in 1895 by the chemist, engineer and industrial Swedish Alfred Nobel (inventor of the dynamite), were first awarded in 1901.
The prize includes a monetary reward of 11 million Swedish crowns (about 1 million euros).
