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Autologous exosomes have gained prominence in regenerative medicine, especially among celebrities such as , and aesthetics as one of the most promising cell therapies today. Extracted from the patient’s own blood, these small cellular vesicles carry proteins, lipids and genetic material capable of stimulating tissue regeneration.
Other Hollywood stars, such as Gwyneth Paltrow and, as well as celebrities such as Kim Kardashian, more recently, are examples of celebrities who have adopted the method with a view to rejuvenating and caring for their skin.
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These microscopic extracellular vesicles are naturally produced by various cells in the body. They contain micro RNA’s, proteins and lipids that can positively influence cellular behavior. When extracted from patients themselves, exosomes are called autologous, eliminating the risk of immunological rejection.
Debates between specialists
However, amid growing interest, treatment with autologous exosomes is still a subject of debate among experts. This regenerative therapy, which uses exosomes derived from the patient’s own cells to rejuvenate the skin, still faces questions regarding its effectiveness and the real capacity to extract these microparticles by currently existing technologies.
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Autologous exosomes: discover the treatment that won over celebrities such as Brad Pitt and Demi Moore
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which restricts them to topical use. Therefore, based on this classification and according to the Brazilian Society of Dermatology, such products, when not autologous, cannot be applied in injectable therapies, regardless of the technique, indication, technical competence of the prescriber or the quality of the product.
In dermatology, autologous exosomes are used in the treatment of androgenetic alopecia, acne scars, melasma and facial rejuvenation. They stimulate collagen production, as well as improving skin texture and promoting hair growth.
Opinion of those who understand the subject
For dermatologist Ana Carolina Sumam, exosome therapy is recent and, despite favorable evidence of its effectiveness, it is necessary to monitor its evolution and studies on the treatment.
“The results are especially notable in the treatment of improving skin quality and treating hair loss. However, studies related to this equipment are constantly being updated. Therefore, it is necessary to be cautious and link its use in accordance with the recommendations of authority bodies”, he stated.
Although recent in Brazil, the use of autologous exosomes is not new in places such as Asia, Europe and the United States. Local researchers have previously explored these structures especially in centers dedicated to regenerative biotechnology.
More treatment details
The treatment stands out for its biocompatibility. Because they are derived from the body itself, autologous exosomes pose minimal risk of allergic reactions or rejection. Furthermore, they stimulate angiogenesis, cell proliferation and extracellular matrix synthesis.
Despite this, like other treatments, autologous exosomes are not miraculous. For Ana Carolina Sumam, this mistaken perception can generate unrealistic expectations in patients: “Exosomes have specific indications and limitations that must be respected. Each case needs to be evaluated individually to determine whether the patient is a candidate for treatment”, she explained.
Among the contraindications, individuals with active infections, severe skin conditions or allergies to specific components should avoid treatment: “It is very important that the patient who falls within these restrictions respects the recommendations. Furthermore, it is advisable to always discuss the medical history with the professional before starting treatment”, concluded the specialist.
