Scientists have been able to confirm that depression is directly related to the development of dementia. In a new study, they identified six symptoms in middle age that can predict this serious disease more than two decades before it develops. , the team believes that their treatment could lead to a reduction in the risk of dementia in the future.
- Scientists have shown a link between depression and the development of dementia.
- The research involved analyzing data from 5,811 middle-aged people.
- The study identified six symptoms that can predict dementia up to two decades ahead.
In research published in the journal The Lancet Psychiatry, researchers from the UK’s University College London analyzed health data from 5,811 middle-aged people, who were predominantly male and white.. Symptoms of depression were recorded through a questionnaire when the participants did not yet have dementia. Finally, they followed their health for the next 25 years.
During the research, 10% of the participants developed dementia. Further analysis showed that persons who were classified as depressed in middle age they had a 27% higher risk of developing dementia. The researchers found that this significant increase in risk was due to six symptoms in adults younger than 60 years. These included:
- Loss of confidence
- Inability to face problems
- Inability to feel affection for others
- Feelings of nervousness and internal tension
- Dissatisfaction with the way tasks are performed
- Difficulty concentrating
Scientists have discovered symptoms of depression that increase the risk of dementia. (illustrative photo)
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In comparison, the researchers found that other symptoms of depression, such as low mood, suicidal thoughts, and sleep problems, had no significant long-term association with dementia. “Our findings suggest that the risk of dementia is not related to depression per se. This approach gives us a much clearer picture of who may be more vulnerable decades before the disease develops,” said lead study author Philipp Frank.
Researchers say targeting these six key symptoms when treating depression could reduce the risk of dementia in the future. “Common problems that many people experience in middle age hide important information about long-term brain health. Observing these patterns could open up new possibilities for early prevention,” stated the lead author.
Doctors warn that the impact of dementia goes beyond cognitive decline. The disease increases the risk of various serious health problems, including infections or cardiovascular problems. There is no known cure for dementia, but patients are recommended therapies that can help relieve symptoms and potentially slow its progression.
