A new research has discovered a correlation between taking metformin and a 30% increase in the likelihood of women with type 2 diabetes to reach 90 years of age.
Metformin, a medication widely used for diabetes, can also prolong the life expectancy of elderly women.
According to a new published in the Journal of Gerontology: Medical Sciences, women with type 2 diabetes who took Metformin had 30% more likely to reach 90 yearscompared to those using an alternative diabetes drug, sulfonylurea.
The study analyzed data from a long-term research project in the United States that involved postmenopausal women. The investigators compared the records of 438 womenhalf of which had been treated with metformin and half with sulphonylureas.
Although recognizing the limitations of the study, including the lack of random assignment and a relatively small sample size, scientists say the findings align with previous evidence of the anti-aging potential broader metformin.
“We found that the onset of metformin treatment increased exceptional longevity compared to the beginning of sulfonylurea treatment among women with type 2 diabetes,” says the authors.
The drug, used for decades to control type 2 diabetes, is classified as a gerotherapeutic, a medicine that can slow aging processes in the body. Has been associated with Reduction of Harm in DNAimproving genetic expression related to longevity and even protection against cognitive decline and long covid, reports.
Although this study does not establish causality, its long period of follow -up, with a average from 14 to 15 years, It has allowed investigators to observe health results at an advanced age, unlike traditional controlled random trials (RCT), which are often shorter in duration.
“This long-term monitoring, from half-aged to 90 years or more, It would not be viable In typical random controlled tests, ”says the study.
Despite these promising results, researchers underline the need for further investigation, ideally through controlled random trials, to confirm the connection between metformin and increased longevity.
